Science | ||||
UK scientists for the first time cure paralysis of the arms
Kounteya Sinha,TNN | May 21, 2014, 03.07 PM ISTRELATED
LONDON: British scientists have for the first time successfully cured paralysis of the arms.
They restored the ability to grasp with a paralyzed hand using spinal cord stimulation.
There is currently no cure for upper limb paralysis, where there has been damage to the nerves which send messages to the muscles from the brain, such as happens after a stroke or spinal injury.
But now researchers at Newcastle University, working with macaque monkeys, have shown that by connecting the brain to a computer and then the computer to the spinal cord, it is possible to restore movement. The discovery opens up the possibility of new treatments within the next few years which could help stroke victims or those with spinal cord injuries regain some movement in their arms and hands.
The team first trained the primates to grasp and pull a spring-loaded handle. The monkeys were then temporarily paralyzed using a drug that wore off after about two hours. During that time the monkey had no movement in their hand and was unable to grasp, even though most of the brain was functioning normally. But when the stimulation circuit was switched on the monkey was able to control its own arm and pull the handle.
Dr Andrew Jackson from Newcastle University and Dr Jonas Zimmermann, now at Brown University, led the research.
Dr Jackson said "When someone has a damaged motor cortex or spinal cord the problem is that the signal from the brain to the muscles isn't getting through. What we have done here is restore that connection, to allow the signal telling the hand to move to reach the spinal cord. By exploiting surviving neural networks below the injury, we can activate natural actions like grasping using just a few stimulation sites. This is the first time that anyone has done that".
The next stage will be to further develop the technology to eventually have a small implant for use in patients that can then form the link between the brain and the muscles.
Dr Jackson added "Much of the technology we used for this is already being used separately in patients today, and has been proven to work. We just needed to bring it all together. I think within five years we could have an implant which is ready for people. And what is exciting about this technology is that it would not just be useful for people with spinal injuries but also people who have suffered from a stroke and have impaired movement due to that. There are some technical challenges which we have to overcome, as there is with any new technology, but we are making good progress".
Dr Zimmermann said "Animal studies such as ours are necessary to demonstrate the feasibility and safety of procedures before they can be tried in human patients, to minimize risk and maximize chance of successful outcomes".
Dr John Williams, head of neuroscience at the Wellcome Trust said "Being able to restore dexterous hand movements to patients paralyzed by stroke or spinal cord injury would be a huge improvement to their independence and quality of life. When used alone or in combination with other rehabilitation approaches, this technique could lead to significant improvements in hand function and transform the lives of paralyzed patients".
They restored the ability to grasp with a paralyzed hand using spinal cord stimulation.
There is currently no cure for upper limb paralysis, where there has been damage to the nerves which send messages to the muscles from the brain, such as happens after a stroke or spinal injury.
But now researchers at Newcastle University, working with macaque monkeys, have shown that by connecting the brain to a computer and then the computer to the spinal cord, it is possible to restore movement. The discovery opens up the possibility of new treatments within the next few years which could help stroke victims or those with spinal cord injuries regain some movement in their arms and hands.
The team first trained the primates to grasp and pull a spring-loaded handle. The monkeys were then temporarily paralyzed using a drug that wore off after about two hours. During that time the monkey had no movement in their hand and was unable to grasp, even though most of the brain was functioning normally. But when the stimulation circuit was switched on the monkey was able to control its own arm and pull the handle.
Dr Andrew Jackson from Newcastle University and Dr Jonas Zimmermann, now at Brown University, led the research.
Dr Jackson said "When someone has a damaged motor cortex or spinal cord the problem is that the signal from the brain to the muscles isn't getting through. What we have done here is restore that connection, to allow the signal telling the hand to move to reach the spinal cord. By exploiting surviving neural networks below the injury, we can activate natural actions like grasping using just a few stimulation sites. This is the first time that anyone has done that".
The next stage will be to further develop the technology to eventually have a small implant for use in patients that can then form the link between the brain and the muscles.
Dr Jackson added "Much of the technology we used for this is already being used separately in patients today, and has been proven to work. We just needed to bring it all together. I think within five years we could have an implant which is ready for people. And what is exciting about this technology is that it would not just be useful for people with spinal injuries but also people who have suffered from a stroke and have impaired movement due to that. There are some technical challenges which we have to overcome, as there is with any new technology, but we are making good progress".
Dr Zimmermann said "Animal studies such as ours are necessary to demonstrate the feasibility and safety of procedures before they can be tried in human patients, to minimize risk and maximize chance of successful outcomes".
Dr John Williams, head of neuroscience at the Wellcome Trust said "Being able to restore dexterous hand movements to patients paralyzed by stroke or spinal cord injury would be a huge improvement to their independence and quality of life. When used alone or in combination with other rehabilitation approaches, this technique could lead to significant improvements in hand function and transform the lives of paralyzed patients".
See realtime coverage |
NEW DELHI: For 11 billion years after its formation through the Big Bang, the Universe had fever - its temperature was rising. Then the fever broke and it started cooling.
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alcohol binge is more dangerous than previously thought."
19th May 5:04 PM
Fine
19° / 10°
Auckland
A single alcohol binge causes bacteria to leak from the gut, leading to increased levels of toxins in the blood.
Photo / Thinkstock
Unwinding in the pub on a Friday night could be wrecking your health -
just four glasses of wine is enough to cause lasting damage, scientist
have found.
A single alcohol binge causes bacteria to leak from the gut, leading to increased levels of toxins in the blood, according to a study carried out the University of Massachusetts Medical School (UMASS).
And the damage could be caused by fewer drinks than you think - researchers classed a binge as four or more alcoholic drinks for women and five or more for men, consumed over a roughly two-hour period.
Professor Gyongyi Szabo, who led the research, said: "We found that a single alcohol binge can elicit an immune response, potentially impacting the health of an otherwise healthy individual.
"Our observations suggest that an alcohol binge is more dangerous than previously thought."
To assess the negative impacts of binge drinking, 11 men and 14 women were given enough alcohol to raise their blood alcohol concentration (BAC) to at least 0.08g/dl in the space of an hour.
Blood samples were then taken for every 30 minutes for four hours after and then again 24 hours later.
The results, published in the journal PLOS ONE, showed that just one alcohol binge led to a rapid increase in endotoxins in the blood - these cause the body to produce immune cells involved in fever, inflammation and tissue destruction.
The researchers also found evidence of bacterial DNA in the bloodstream, showing that bacteria had entered the gut. It is then able to travel through the gut walls to other parts of the body.
Women had higher blood alcohol levels compared to men, as well as higher endotoxin levels.
Greeter gut permeability and increased endotoxin levels have previously been linked to many of the health problems associated with alcohol consumption, including liver disease.
- Independent
4 glasses of wine is enough to harm your health, scientists say
11:30 AM Monday May 19, 2014
A single alcohol binge causes bacteria to leak from the gut, leading to increased levels of toxins in the blood, according to a study carried out the University of Massachusetts Medical School (UMASS).
And the damage could be caused by fewer drinks than you think - researchers classed a binge as four or more alcoholic drinks for women and five or more for men, consumed over a roughly two-hour period.
Professor Gyongyi Szabo, who led the research, said: "We found that a single alcohol binge can elicit an immune response, potentially impacting the health of an otherwise healthy individual.
"Our observations suggest that an alcohol binge is more dangerous than previously thought."
To assess the negative impacts of binge drinking, 11 men and 14 women were given enough alcohol to raise their blood alcohol concentration (BAC) to at least 0.08g/dl in the space of an hour.
Blood samples were then taken for every 30 minutes for four hours after and then again 24 hours later.
The results, published in the journal PLOS ONE, showed that just one alcohol binge led to a rapid increase in endotoxins in the blood - these cause the body to produce immune cells involved in fever, inflammation and tissue destruction.
The researchers also found evidence of bacterial DNA in the bloodstream, showing that bacteria had entered the gut. It is then able to travel through the gut walls to other parts of the body.
Women had higher blood alcohol levels compared to men, as well as higher endotoxin levels.
Greeter gut permeability and increased endotoxin levels have previously been linked to many of the health problems associated with alcohol consumption, including liver disease.
- Independent
WASHINGTON:
US doctors claim to have wiped out a woman's advanced blood cancer with
a massive dose of the measles vaccine, enough to inoculate 10 million
people.
|
WASHINGTON:
In a breakthrough, Harvard scientists have discovered that stem cells
loaded with the herpes virus can be used to specifically target and kill
brain tumours.
|
Sun got a mysterious hole: Nasa
IANS | May 13, 2014, 12.35 PM IST
It appears dark in extreme ultraviolet light as there is less material to emit in these wavelengths.
CALIFORNIA: A mysterious squarish hole in our sun from where solar wind
is streaming out at a super fast speed has been captured. Luckily for
us, it is positioned so far south on the sun that there is less chance
that the solar wind stream will impact the earth.
The coronal hole is clearly visible as the sun rotates, appearing to be a black abyss into the centre of the sun, Nasa reported.
In the Nasa video, the massive hole appears to flicker and spark as it rotates past the camera.
Such holes may appear at any time of the solar cycle but they are most common during the declining phase of the cycle.
"A coronal hole, almost square in its shape, is one of the most noticeable features on the sun of late," the space agency said in a statement.
It appears dark in extreme ultraviolet light as there is less material to emit in these wavelengths.
"Inside the coronal hole, you can see bright loops where the hot plasma outlines little pieces of the solar magnetic field sticking above the surface," Nasa added.
Solar flares can damage satellites and have an enormous financial cost.
The charged particles can also threaten airlines by disturbing the earth's magnetic field.
Very large flares can even create currents within electricity grids and knock out energy supplies.
The coronal hole is clearly visible as the sun rotates, appearing to be a black abyss into the centre of the sun, Nasa reported.
In the Nasa video, the massive hole appears to flicker and spark as it rotates past the camera.
Such holes may appear at any time of the solar cycle but they are most common during the declining phase of the cycle.
"A coronal hole, almost square in its shape, is one of the most noticeable features on the sun of late," the space agency said in a statement.
It appears dark in extreme ultraviolet light as there is less material to emit in these wavelengths.
"Inside the coronal hole, you can see bright loops where the hot plasma outlines little pieces of the solar magnetic field sticking above the surface," Nasa added.
Solar flares can damage satellites and have an enormous financial cost.
The charged particles can also threaten airlines by disturbing the earth's magnetic field.
Very large flares can even create currents within electricity grids and knock out energy supplies.
First electric aircraft takes flight
Agencies | May 13, 2014, 05.22 AM IST
First electric aircraft
RELATED
LONDON:
The world's first airplane completely powered by electricity has
successfully taken to the skies for its maiden flight, and could bring
down air travel cost by more than a third, its developer Airbus said.
The small experimental aircraft called 'E-Fan' carried its first flight at an airport near Bordeaux in southwestern France, and could prove to be a key step towards greener, quieter and cheaper air travel. Manufactured by Toulouse-based Airbus, E-Fan measures little more than 19 feet from nose to tail and makes slightly more noise than a hairdryer.
Powered by 120 lithium-ion polymer batteries, the plane's first official flight last month lasted less than 10 minutes, though the plane has the capability to fly for around an hour before recharging. An hour-long commercial flight with the E-Fan, according to Airbus, could cost only $16, compared to $55 for a flight in a petrol-powered plane of the same size, 'Inhabitat.com' reported.
The electric E-Fan training aircraft is a highly innovative technology experimental demonstrator based on an all-composite construction, Airbus said on its website. "The E-Fan project and Airbus Group's commitment to the field of electric and hybrid research show our vision of future technological developments," said said Airbus Group chief technical officer Jean Botti.
"It will not only lead to a further reduction in aircraft emissions and noise to support our environmental goals but will also lead to more economic and efficient aircraft technology in the long run," said Botti.
Airbus plans to manufacture two versions of the E-Fan. The two-seater E-Fan 2.0 will be a fully electric training aircraft, while E-Fan 4.0 will be used for both training and general flight purposes and will be powered by a hybrid system, the report said.
Airbus Group and its partners are aiming to perform research and development to construct a series version of the E-Fan and propose an industrial plan for a production facility close to Bordeaux Airport, Airbus said.
The small experimental aircraft called 'E-Fan' carried its first flight at an airport near Bordeaux in southwestern France, and could prove to be a key step towards greener, quieter and cheaper air travel. Manufactured by Toulouse-based Airbus, E-Fan measures little more than 19 feet from nose to tail and makes slightly more noise than a hairdryer.
Powered by 120 lithium-ion polymer batteries, the plane's first official flight last month lasted less than 10 minutes, though the plane has the capability to fly for around an hour before recharging. An hour-long commercial flight with the E-Fan, according to Airbus, could cost only $16, compared to $55 for a flight in a petrol-powered plane of the same size, 'Inhabitat.com' reported.
The electric E-Fan training aircraft is a highly innovative technology experimental demonstrator based on an all-composite construction, Airbus said on its website. "The E-Fan project and Airbus Group's commitment to the field of electric and hybrid research show our vision of future technological developments," said said Airbus Group chief technical officer Jean Botti.
"It will not only lead to a further reduction in aircraft emissions and noise to support our environmental goals but will also lead to more economic and efficient aircraft technology in the long run," said Botti.
Airbus plans to manufacture two versions of the E-Fan. The two-seater E-Fan 2.0 will be a fully electric training aircraft, while E-Fan 4.0 will be used for both training and general flight purposes and will be powered by a hybrid system, the report said.
Airbus Group and its partners are aiming to perform research and development to construct a series version of the E-Fan and propose an industrial plan for a production facility close to Bordeaux Airport, Airbus said.
See realtime coverage |
NASA scientists have recreated, right here on Earth, dust grains similar to those that form in the outer layers of dying stars. A team of researchers at NASA's Ames Research Center in Moffett Field, California, has successfully reproduced the processes that ...
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A Harvard Girl Figured Out How To 3D Print Makeup From Any Home Computer
More :
saiA Harvard Girl Figured Out How To 3D Print Makeup From Any Home Computer And The Demo Is Mindblowing
inShare121
By that, she means color printers are available to everyone, and the ink they have is the same as the ink makeup companies use in their products. She also says the ink is FDA approved.
Choi created a mini home printer, Mink, that will retail for $300 and allow anyone to print makeup by ripping the color code off color photos on the Internet.
She demonstrated how it works, then brushed some of the freshly-printed makeup onto her hand. She answered a lot of the tough questions about how she'll move beyond powders to creamier products and partner with traditional printing companies in the video below.
Here's how Mink, Choi's makeup-printing machine, works.
First, find a color you want to print. Choi says her machine will print creamy lipsticks or powdery eye shadows.
TechCrunch Disrupt
Use the color picker to copy the hex code of the color you've chosen. In this demo, Choi chose pink.
TechCrunch Disrupt
Using Microsoft Paint or Photoshop, paste the hex code into a new document. You'll see the color you want to print pop up.
TechCrunch Disrupt
Print the color, like you'd print any other document on your computer.
TechCrunch Disrupt
Here Choi is, printing out the pink eye shadow.
TechCrunch Disrupt
This is what the finished product looks like. It comes in a little Mink-provided container that looks just like eye shadow.
TechCrunch Disrupt
Choi dips a makeup brush in the freshly-printed powder to show it really is makeup.
TechCrunch Disrupt
Then she brushes the pink on her hand. "Mink enables the web to become the biggest beauty store in the world," says Choi. "We're going to live in a world where you can take a picture of your friend's lipstick and print it out."
TechCrunch Disrupt
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