New compound shrinks pancreatic cancer tumours, according to new study

Sunday, 28 June 2015 - 1:26pm IST | Place: London | Agency: PTI

    Scientists have designed a new chemical compound that has reduced the growth of pancreatic cancer tumours by 80% in treated mice.
    Scientists have designed a new chemicalcompound that has reduced the growth of pancreatic cancer tumours by 80% in treated mice.
    The compound, called MM41, was designed to block faulty genes by targeting little knots in the DNA, called quadruplexes, which are very different from normal DNA and which are especially found in faulty genes. The findings showed that MM41 had a strong inhibiting effect on two genes - k-RAS and BCL-2 - both of which are found in the majority of pancreatic cancers.
    Researchers at the University College London (UCL), led by professor Stephen Neidle, conducted a small-scale trial, treating two groups of eight mice with pancreatic tumours with different doses of MM41 twice a week for 40 days (12 doses). A further control group received no treatment.
    The tumours in the group given the larger dose decreased by an average of 80% during the treatment period, and after 30 days, tumour regrowth stopped in all the mice. For two of the mice in this group, the tumour disappeared completely with no signs of regrowth after treatment ended for a further 239 days (the approximate equivalent to the rest of their natural life span).
    Analysis of the mice tumours showed that the MM41 compound had been taken up into the nucleus of the cancer cells showing that it was able to effectively target the pancreatic cancer tumour. The team also saw no significant side effects on the mice during the study: there was no damage to other tissue or organs, and none of the mice showed any significant weight loss.
    "This research provides a potentially very powerful alternative approach to the way that conventional drugs tackle pancreatic cancer, by targeting a very specific area of the DNA of faulty genes," said Neidle. "One of the genes that MM41 blocks - the BCL-2 gene - is involved in regulating apoptosis, the body's natural process which forces cells to die if they become too damaged or unhealthy to be repaired.
    "BCL-2 is present in high amounts in many tumours and helps cancer cells to survive, but when the BCL-2 gene is blocked by MM41 in mice, the cancer cells succumb to apoptosis and die," said Neidle. Neidle stressed that although these results are exciting, MM41 is not ideal for trialling in humans and further refinements are needed.
    The study was published in the journal Nature Scientific Reports.

    8 jaw-dropping photos from NASA's new image gallery

    Cat's Eye Nebula
    The Cat's Eye Nebula, which is 3,000 light-years from Earth, as captured by the Hubble telescope. (Photo: NASA)
    If you're a fan of incredible space photography, you're going to love the massive new digital gallery NASA just made available.
    Built by Luna Imaging, the gallery is composed of more than 138,000 high-quality shots from 70 collections covering everything from the Apollo missions to the Hubble telescope, Mars rovers, International Space Station and much more. 
    “We envision that NASA Images will appeal to space fans, STEM educators, visual resource fans, archive fans, people who appreciate open collections,” a Luna spokesperson told Gizmodo in an email. “We’ve already had some interest in the site from people with GIS and geospatial interests because of the satellite imagery the collection includes.”
    Below are some beautiful images we located with just a few keyword searches. To have your own look around, hit the gallery here
    1. Supernova N49
    Supernova N49
    Photo: NASA
     
    Located in the Large Magellanic Cloud, N49 is the remains of a supernova that has since transformed into a stringy thing of beauty. It was captured here by the Hubble Space Telescope in 2006.
    2. Mars revealed in stunning detail
    Mars revealed in stunning detail
    Photo: NASA
    In 1976, the world received its clearest view yet of the surface of Mars thanks to hundreds of high-quality photos sent back from NASA's Viking mission to the red planet. Pictured in this shot is Valles Marineris, a 2,500-mile-long mega-canyon that spans some 20 percent of the surface of Mars and reaches depths of more than 4 miles. 
    3. Our place in the Milky Way
    Our place in the Milky Way
    Photo: NASA
    NASA's new gallery also includes access to a number of informative and beautiful artist renditions, like this one marking our place in the Milky Way galaxy. 
    4. Lunar training
    Lunar training
    Photo: NASA
    Some incredible behind-the-scene photos — including this one from 1968 showing a NASA Langley researcher "moon walking" — are also available. 
    5. Space walk rescue system test
    Space walk rescue system test
    Photo: NASA
    In 1994, Astronauts Carl J. Meade and Mark C. Lee performed in an in-space demonstration of a space walk rescue. NASA recently celebrated 50 years of successful space walks with the release of the documentary "Suit Up."
    6. Comet Shoemaker-Levy 9 impacts Jupiter
    Comet Shoemaker-Levy 9 impacts Jupiter
    Photo: NASA
    In the summer of 1994, the world watched as 21 fragments of Comet Shoemaker-Levy 9 slammed in Jupiter, the first direct observation of an extraterrestrial collision of solar system objects. The impacts were massive, but one in particular, that of fragment G, exploded with a power estimated at more than 600 times the world's nuclear arsenal. 
    7. Coronal rain on the sun
    Coronal rain on the sun
    Photo: NASA
    Turns out it does rain on the sun — just not the kind any of us would want to experience. In this photo captured by the orbiting TRACE telescope, coronal rain — plasma riding magnetic waves above the sun's surface — is falling back to the surface as it cools. The average temperature of this "rain"? A searing 107,540 degrees Fahrenheit. 
    8. A view of Earth from Saturn
    Saturns rays
    Photo: NASA
    The pale blue dot, the term coined for the ultimate Earth selfie, continues to amaze as NASA spacecraft move further through the solar system. In this spectacular shot captured by the Cassini spacecraft of Saturn in 2006, we see the planet's stunning array of rings. And then, to the left of the first brightest ring, you see it: a pale blue dot, our home, more than 746 million miles away. 

    Parallel worlds exist and interact with our world, say physicists


    Parallel world
    Do parallel worlds ever cross paths? (Photo: Martin Brigden/flickr)
    Quantum mechanics, though firmly tested, is so weird and anti-intuitive that famed physicist Richard Feynman once remarked, "I think I can safely say that nobody understands quantum mechanics." Attempts to explain some of the bizarre consequences of quantum theory have led to some mind-bending ideas, such as the Copenhagen interpretation and the many-worlds interpretation
    Now there's a new theory on the block, called the "many interacting worlds" hypothesis (MIW), and the idea is just as profound as it sounds. The theory suggests not only that parallel worlds exist, but that they interact with our world on the quantum level and are thus detectable. Though still speculative, the theory may help to finally explain some of the bizarre consequences inherent in quantum mechanics, reports RT.com.
    The theory is a spinoff of the many-worlds interpretation in quantum mechanics — an idea that posits that all possible alternative histories and futures are real, each representing an actual, though parallel, world. One problem with the many-worlds interpretation, however, has been that it is fundamentally untestable, since observations can only be made in our world. Happenings in these proposed "parallel" worlds can thus only be imagined.
    MIW, however, says otherwise. It suggests that parallel worlds can interact on the quantum level, and in fact that they do.
    "The idea of parallel universes in quantum mechanics has been around since 1957," explained Howard Wiseman, a physicist at Griffith University in Brisbane, Australia, and one of the physicists to come up with MIW. "In the well-known ‘Many-Worlds Interpretation’, each universe branches into a bunch of new universes every time a quantum measurement is made. All possibilities are therefore realised – in some universes the dinosaur-killing asteroid missed Earth. In others, Australia was colonised by the Portuguese."
    "But critics question the reality of these other universes, since they do not influence our universe at all," he added. "On this score, our "Many Interacting Worlds" approach is completely different, as its name implies."
    Wiseman and colleagues have proposed that there exists "a universal force of repulsion between ‘nearby’ (i.e. similar) worlds, which tends to make them more dissimilar." Quantum effects can be explained by factoring in this force, they propose.
    Whether or not the math holds true will be the ultimate test for this theory. Does it or does it not properly predict quantum effects mathematically? But the theory is certain to provide plenty of fodder for the imagination.
    For instance, when asked about whether their theory might entail the possibility that humans could someday interact with other worlds, Wiseman said: "It's not part of our theory. But the idea of [human] interactions with other universes is no longer pure fantasy."
    What might your life look like if you made different choices? Maybe one day you'll be able to look into one of these alternative worlds and find out.
    Related on MNN:

    Stomach cancer will be detected in a jiffy


    Stomach cancer will be detected in a jiffy
     Stomach cancer will be detected in a jiffy
    (Getty Images)
    British researchers have developed a breath test that can detect oesophageal and gastric (stomach) cancer in minutes with 90 percent accuracy.

    The test has produced encouraging results in a clinical study of 210 patients, and will now be tested in a larger trial involving three hospitals in London.

    Oesophageal and gastric malignancies account for 15 percent of cancer-related deaths globally.

    Doctors diagnose oesophageal and gastric cancers by carrying out an endoscopy. This is a procedure where the inside of the body is examined using a probe with a light source and video camera at the end via the mouth and down the gullet.

    However, the procedure is invasive and expensive. Moreover, only two percent of patients who are referred for an endoscopy by GPs are diagnosed with oesophageal or gastric cancer.

    "Our breath test could address these problems because it can help diagnose patients with early non-specific symptoms as well as reduce the number of invasive endoscopies carried out on patients, which often lead to negative results," said lead author of the study George Hanna from Imperial College London.

    "Diagnosis at an early stage could give patients more treatment options and ultimately save more lives," Hanna noted.

    The test looks for chemical compounds in exhaled breath that are unique to patients with oesophageal and gastric cancer.

    The cancers produce a distinctive smell of volatile organic compounds (VOC), chemicals that contain carbon and are found in all living things, which can help doctors detect early signs of the disease.

    To take the test, patients breathe into a device similar to a breathalyzer which is connected to a bag.

    The compounds in their exhaled breath are analyzed by a selected ion flow tube mass spectrometer.

    The researchers used breath samples of patients with oesophageal and gastric cancer from 2011 to 2013.

    The study was published in the journal Annals of Surgery.

    This is what high heels do to your feet


    This is what high heels do to your feet



    This is what high heels do to your feet
    This is what your high heels are doing to your feet (Getty Images)
    Did you know that high heels are the culprit behind the rise in the number of middle aged women experiencing an agonizing foot condition that is compared to "walking on razors blades?"

    Researchers claim that the number of people experience Morton's neuroma, which is a condition that disturbs the nerves running between the toes, has doubled in the past 10 years, reported the Independent.

    Moreover, this condition occurs when fibrous tissue develops around a specific nerve in the foot which becomes irritated and compressed and high heels have been blamed for the agonizing foot pain with the largest group of suffers being women aged between 40 and 69.

    It is being said that this condition is thought to be brought on from years of wearing high heeled or ill-fitting shoes which push the foot bone against the nerve.

    Orthopaedic Andrew Craig said that they have known for a long time that the condition seems to predominantly affect females of a middling age, with speculation that high heels and other such tightly fitting and unnatural footwear.

    He added that increasing awareness of Morton's neuroma can only be a good thing, not least because numbness in the foot could be a sign of other, potentially life-altering conditions, such as diabetes.

    Craig's research explored how well various treatments for the condition work including, insoles and steroid injections usage.
    -----------------------------------------------------------------------------------------------------------------------


    Plant inspired solar cells to revolutionise energy storage



    Plant inspired solar cells to revolutionise energy storage
    (Representative image)
    NEW YORK: A new technology developed by scientists at University of California, Los Angeles (UCLA) can store solar energy for up to several weeks; an advance that could change the way scientists think about designing solar cells.

    The materials in most of today's residential rooftop solar panels can store energy from the sun for only a few microseconds at a time.

    The new design is inspired by the way that plants generate energy through photosynthesis.

    "In photosynthesis, plants that are exposed to sunlight use carefully organised nanoscale structures within their cells to rapidly separate charges, pulling electrons away from the positively charged molecule that is left behind, and keeping positive and negative charges separated," said senior study author Sarah Tolbert.

    "That separation is the key to making the process so efficient," Tolbert said.

    To capture energy from sunlight, conventional rooftop solar cells use silicon, a fairly expensive material.

    On the other hand, plastic solar cells which are cheaper - are relatively inefficient, because the separated positive and negative electric charges often recombine before they can become electrical energy.

    "Modern plastic solar cells don't have well-defined structures like plants do. But this new system pulls charges apart and keeps them separated for days, or even weeks," Tolbert said.

    "Once you make the right structure, you can vastly improve the retention of energy," she added.

    The two components that make the UCLA developed system work are a polymer donor and a nano-scale fullerene acceptor.

    The polymer donor absorbs sunlight and passes electrons to the fullerene acceptor. The process generates electrical energy.

    The plastic materials, called organic photovoltaics, are typically organised like a plate of cooked pasta a disorganised mass of long, skinny polymer 'spaghetti' with random fullerene 'meatballs.'

    But this arrangement makes it difficult to get current out of the cell because the electrons sometimes hop back to the polymer spaghetti and are lost.

    The UCLA technology arranges the elements more neatly like small bundles of uncooked spaghetti with precisely placed meatballs.

    Some fullerene meatballs are designed to sit inside the spaghetti bundles, but others are forced to stay on the outside.

    The fullerenes inside the structure take electrons from the polymers and toss them to the outside fullerene, which can effectively keep the electrons away from the polymer for weeks.

    "When the charges never come back together, the system works far better," another senior author Benjamin Schwartz said.

    In the new system, the materials self-assemble just by being placed in close proximity.

    The new design is also more environment-friendly than current technology, because the materials can assemble in water instead of more toxic organic solutions that are widely used today, the researchers said.

    The findings were published in the journal Science.

    Mars Orbiter Mission enters 100th orbit around Mars



    Mars Orbiter Mission enters 100th orbit around Mars
    Mars Orbiter Mission entered the 100th orbit around the Red Planet on Monday.
    MUMBAI: India's Mars Orbiter Mission (MOM) entered its 100th orbit around the Red Planet on Monday.

    According to Isro, the spacecraft will take about three-and-a-half days to complete the orbit that will end on Thursday.

    Launched on November 5, 2013, Rs 450-crore MOM entered the Martian orbit on September 24, 2014.

    Isro stated that the spacecraft, which entered a communication blackout period on June 8, is gradually emerging out of that phase and has begun transmitting data to ground stations. The pause took place because the Sun came between Earth and Mars, which happens once in 26 months.

    The current elliptical orbit of the spacecraft has a periareon (the point nearest to the Mars surface) of 474km and an apoareion (the farthest point) of 71,132km.

    The five payloads on board were last operated in May 2015 and their performance was satisfactory. The Mars Colour Camera has so far taken 405 images. The remaining four payloads will be gradually reactivated in the coming weeks.

    Isro chairman A S Kiran Kumar told the media last week in New Delhi that data from the other four payloads was being reviewed and analyzed and will be made public "in due course".

    The spacecraft was designed for a mission life of six months in Mars orbit and this was completed on March 24, 2015. With this the primary objectives of MOM have been realized.

    A new Isro app called Sakaar, launched last week, allows Android mobile users to have a 3-D view of MOM and its various aspects as well as some of the other Isro missions. 
    COMMENT-
    WHY PAKISTAN  NOT IN SPACE RACE?BECAUSE CHINA WILL NOT GIVE THAT TECHNOLOGY TO A TERRORIST STATE 
    [ATOMIC TECH WAS GIVEN BY C.I.A.
    ROCKET TECH GIVEN BY NORTH KOREA AND CHINA] 


    No Comparison With Indian Space Technology | Pakistani General ...
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    No Comparison With Indian Space Technology | Pakistani General
    india vs pakistan comparison 2015

    Assanas are no better than running around the track


    With the UN-backed International Yoga Day on Sunday, which apparently has made into the Guinness Book of records for its sheer numbers, Indians who are proud of the country’s ancient past can be gratified that the world has seen it. The day was indeed unprecedented because such a public display of people stretching and bending in large numbers in world capitals was new.
    That India, or rather the Prime Minister Narendra Modi, was the force behind this global spectacle will certainly make a lot of Indians proud. It was him, who had urged the UN General Assembly in 2014 to set aside a day for yoga. Subsequently, India’s resolution on the proposal drew the largest ever number of cosponsors in the General Assembly. Leading the show in Dehli on Sunday, he said: “I believe that from the 21st of June, through the International Day of Yoga, it is not just the beginning of a day but the beginning of a new age through which we will achieve greater heights of peace, good will and train the human spirit.”
    Most of the mainstream media went into an overdrive with anchors, experts, celebrities and politicians claiming how great Yoga is. Most of them said its practice kept them fit, while hardcore fans claimed that it was effective against a lot of illnesses from cancer to hypertension. What was however, unanswered in the excitement and hype, was how different it was from other forms of exercises in terms of results. Barring the personal testimonies of its diehard fans, many of whom also believed that ancient India was the repository of even modern scientific and technological knowledge, the mainstream media hardly presented any scientific evidence to demonstrate the superiority of Yoga. Neither were there any counter-views. It was a one-sided revelry that bolstered the Indian fantasy of a super power.
    PTI image.
    PTI image.
    Not that Yoga is not beneficial. Nobody says that. People feel good and healthy doing it. But a lot of others, who do regular exercises also feel the same. Those who run, cycle and do weight training also vouch for the “high”, the rush of endorphins, they get. There may be several more millions engaged in exercises such as walking, running, cycling, stretching and weight training than those practising Yoga and reaping equal or better benefits - but they don’t make a single cohort because there is no brand that unifies them as Yoga does and there is no allure of spirituality and “5000 years” of heritage behind what they do.
    Here’s where scientific enquiry must play an important part. Other than being a good exercise, does it really have the healing powers as many claim. The best way to answer these claims are Randomised Control Trials (RCT) than personal testimonies. RCTs, which are the gold standard for clinical trials, in simplest terms means a study (with random sampling) in which people receiving treatment (Yoga, in this case), called treatment group, are compared with those who don’t receive it, called control group. (To know if Yoga is better than other forms of exercises, the treatment group should be Yoga practitioners and the control group, people who are doing other exercises.)
    Although a lot of RCTs have been done for Yoga, for the tall therapeutic claims its apostles make, the body of work is quite limited. And importantly, the results are far from impressive. At best, the trials show nothing more than some benign, positive signs. It’s impossible to do a meta-analysis in a media column, but let’s take a look at some of the RCTs published in reputed, peer-reviewed journals.
    One of the common ailments that Yoga seems to help is lower back pain. A lot of people vouch for it, but what has scientific studies say? According to this RCT in the Journal of American Medical Association (JAMA), it’s not more effective than stretching exercises. In fact, the study says:”Yoga classes were more effective than a self-care book, but not more effective than stretching classes, in improving function and reducing symptoms due to chronic low back pain, with benefits lasting at least several months.”
    Asthma is another common illness that Yoga apparently alleviates. Does it really help? Take a look at this 2014 study in the journal “Annals of Allergy, Asthma and Immunology”, which took into account the results of 14 RCTs. And the result? “Yoga cannot be considered a routine intervention for asthmatic patients at this point. It can be considered an ancillary intervention or an alternative to breathing exercises for asthma patients interested in complementary interventions.”
    What it practically says is that Yoga doesn’t hurt, but it doesn’t help either. A Cochrane (a global medical research network that academics and medical practitioners rely on) review in 2013 was even more direct, when it said that “no conclusive evidence in this review supports or refutes the efficacy of such intervention in the treatment of adult patients with asthma.”
    It doesn’t help in arthritis, another great reason to practice Yoga for many, either. This German study, which analysed eight RCTs, in Oxford Rheumatology journal finds no reason to suggest even ancillary use of Yoga for osteoarthritis, rheumatoid arthritis and fibromyalgia, the common arthritic diseases.
    Now, the bigger claim - cancer. This study  published in The Journal of Clinical Oncology in 2007 did find that Yoga improved emotional well-being and mood among breast cancer survivors, not their survival rate or treatment effectiveness. However, the huge limitation of the study is that it compared people doing yoga with people not doing it, not with people doing some other form of exercise.
    So, the summary of the story is that there is no conclusive evidence that demonstrates Yoga’s health benefits or its superiority over other forms of structured exercises. As this Scientific American article notes, any form of regular exercise gives one a high, makes one feel physically and mentally good, and less stressful.
    There’s no denying the fact that Yoga is popular all over the world, but what drives it is its commercialisation and the sex-appeal as a spiritual-lifestyle fad. In the US alone, it’s a 27 billion dollar industry and its popular image is that of a slender and taut female, as this Huffington Post article notes”. The yoga body is Gwyneth Paltrow's body -- the elongated feminine form.” How true!
    Therefore, the numbers of people and countries that made some Indians proud on Sunday doesn’t mean much because, it’s a free brand of pop-spirituality and exercise that thousands of entrepreneurs cash in on. India’s call for a UN day for the brand is great news for them, because it means free publicity and more money. Mobilising people to the streets to do those fancy stretches (unlike in India where people with ungainly paunches were struggling) is in their interest.
    If it’s about real numbers and relevance to contemporary India, what the country should celebrate is the UN’s World Toilet Day, because we have nearly two-third of the world’s open defecators and half of our fellow citizens do it openly, often shamelessly in groups. By revelling in reflected glory of the global popularity of Yoga, we are not only escaping to an imaginary past to cover up our failures, but are also indulging in yet another round of delusional cultural revivalism for political reasons.

    New gene identified in women with mental illness

    Washington, June 21 (IANS): In a significant finding that may lead to easier diagnoses and new treatment options, researchers have identified a particular gene whose over-production could be a diagnostic indicator of mental illness in female psychiatric patients.
    The gene XIST, which is responsible for inactivating one of the two copies of the X chromosome in cells that store genetic material, works overtime in female patients with mental illnesses, such as bipolar disorder, major depression and schizophrenia.
    Over-production of XIST and genes from the inactive X chromosome are common denominators in the development of psychiatric disorders in patients with rare chromosome disorders.
    Reversing the abnormal activity of the inactive X chromosome in patients suffering from mental illness may offer a potential new strategy for treating psychiatric disorders.
    "There has been an utmost urgency to identify biomarkers for mental illness that could significantly impact research and drug development," said lead author Xianjin Zhou, assistant professor in the department of psychiatry at at University of California, San Diego School of Medicine.
    The study was conducted on 60 lymphoblastoid cell lines from female patients, most of whom had a family history of mental illness.
    Approximately 50 percent of the female patients exhibited abnormally higher level of XIST and other genes related to the X chromosome.
    "Our results indicate that a large subpopulation of female psychiatric patients from the general population may have abnormal function of the inactive X chromosome," said Zhou pointed out.
    "These results are powerful in that early diagnosis of mental illness could possibly happen with a simple blood test, leading to better interventions, therapy and treatment options," Zhou concluded.
    The study was published this week in the journal EbioMedicine.

    Gene that may reverse colorectal cancer identified

    Business Standard - ‎3 hours ago‎
    Colorectal cancer cells may be coaxed to turn back into normal tissue simply by reactivating a single gene, scientists say. Researchers found that restoring normal levels of a human colorectal cancer gene in mice stopped tumour growth and re-established ...

    What's on the surface of a black hole?

    What's on the surface of a black hole? by Pam Frost Gorder for OSU News Columbus OH (SPX) Jun 17, 2015


    Simulated view of a black hole by Alain Riazuelo of the French National Research Agency.
    Are black holes the ruthless killers we've made them out to be? Samir Mathur says no. According to the professor of physics at The Ohio State University, the recently proposed idea that black holes have "firewalls" that destroy all they touch has a loophole.
    In a paper posted online to the arXiv preprint server [arXiv:1506.04342], Mathur takes issue with the firewall theory, and proves mathematically that black holes are not necessarily arbiters of doom. In fact, he says the world could be captured by a black hole, and we wouldn't even notice.
    More than a decade ago, Mathur used the principles of string theory to show that black holes are actually tangled-up balls of cosmic strings. His "fuzzball theory" helped resolve certain contradictions in how physicists think of black holes.
    But when a group of researchers recently tried to build on Mathur's theory, they concluded that the surface of the fuzzball was actually a firewall.
    According to the firewall theory, the surface of the fuzzball is deadly. In fact, the idea is called the firewall theory because it suggests that a very literal fiery death awaits anything that touches it.
    Mathur and his team have been expanding on their fuzzball theory, too, and they've come to a completely different conclusion. They see black holes not as killers, but rather as benign copy machines of a sort.
    They believe that when material touches the surface of a black hole, it becomes a hologram, a near-perfect copy of itself that continues to exist just as before.
    "Near-perfect" is the point of contention. There is a hypothesis in physics called complementarity, which was first proposed by Stanford University physicist Leonard Susskind in 1993. Complementarity requires that any such hologram created by a black hole be a perfect copy of the original.
    Mathematically, physicists on both sides of this new fuzzball-firewall debate have concluded that strict complementarity is not possible; That is to say, a perfect hologram can't form on the surface of a black hole.
    Mathur and his colleagues are comfortable with the idea, because they have since developed a modified model of complementarity, in which they assume that an imperfect hologram forms. That work was done with former Ohio State postdoctoral researcher David Turton, who is now at the Institute of Theoretical Physics at the CEA-Saclay research center in France.
    Proponents of the firewall theory take an all-or-nothing approach to complementarity. Without perfection, they say, there can only be fiery death.
    With his latest paper, Mathur counters that he and his colleagues have now proven mathematically that modified complementarity is possible.
    It's not that the firewall proponents made some kind of math error, he added. The two sides based their calculations on different assumptions, so they got different answers. One group rejects the idea of imperfection in this particular case, and the other does not.
    Imperfection is common topic in cosmology. Physicist Stephen Hawking has famously said that the universe was imperfect from the very first moments of its existence. Without an imperfect scattering of the material created in the Big Bang, gravity would not have been able to draw together the atoms that make up galaxies, stars, the planets--and us.
    This new dispute about firewalls and fuzzballs hinges on whether physicists can accept that black holes are imperfect, just like the rest of the universe.
    "There's no such thing as a perfect black hole, because every black hole is different," Mathur explained.
    His comment refers to the resolution of the "information paradox," a long-running physics debate in which Hawking eventually conceded that the material that falls into a black hole isn't destroyed, but rather becomes part of the black hole.
    The black hole is permanently changed by the new addition. It's as if, metaphorically speaking, a new gene sequence has been spliced into its DNA. That means every black hole is a unique product of the material that happens to come across it.
    The information paradox was resolved in part due to Mathur's development of the fuzzball theory in 2003. The idea, which he published in the journal Nuclear Physics B in 2004, was solidified through the work of other scientists including Oleg Lunin of SUNY Albany, Stefano Giusto of the University of Padova, Iosif Bena of CEA-Saclay, and Nick Warner of the University of Southern California. Mathur's co-authors included then-students Borun Chowdhury (now a postdoctoral researcher at Arizona State University), and Steven Avery (now a postdoctoral researcher at Brown University).
    Their model was radical at the time, since it suggested that black holes had a defined--albeit "fuzzy"--surface. That means material doesn't actually fall into black holes so much as it falls onto them.
    The implications of the fuzzball-firewall issue are profound. One of the tenets of string theory is that our three-dimensional existence--four-dimensional if you count time--might actually be a hologram on a surface that exists in many more dimensions.
    "If the surface of a black hole is a firewall, then the idea of the universe as a hologram has to be wrong," Mathur said.
    The very nature of the universe is at stake, but don't expect rival physicists to come to blows about it.
    "It's not that kind of disagreement," Mathur laughed. "It's a simple question, really. Do you accept the idea of imperfection, or do you not?"


    WHAT IS ON THE SURFACE OF ANY HOLE?
    DEPENDS ON WHICH HOLE 





     nasa-black.jpg
    www.ibtimes.co.uk
    If Earth hit the surface of a black hole 'it would become a hologram copy and continue to exist'
     
     
     
     The Difference Between Black & White Holes: — From Quarks to Quasars
    www.fromquarkstoquasars.com
    Via NASA/FQtQ Jolene Creighton
     
     
     READ OF SUCH A CONTRAPTION SEEN IN ASTRO PROJECTON

    THE PERSON WHO SAW IT IN THE EXTRATERRESTRIAL SPACE FOUND IT EMITTING ENERGY -UNLIMITED ENERGY FROM THE SINGULARITY AT THE CENTRE
     
     
     
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     MAY BE THE TUNNEL SEEN IN N.D.E .EXPERIENCES
     
     
      Presentation Name on emaze
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    One possibility is that white holes might be “glued” to black holes.