Short-Sleeved Solar Powered Air Conditioning Clothing
Cloth material: Decron
Duration of continuous work: 8-10 hours (5V)
Tip: Customization is OK
Long-Sleeved Solar Powered Air Conditioning Clothing
Cloth material: Decron
Duration of continuous work:8- hours (5V)
Tip: Customization is OK
#2 – Solar Powered Cooling Helmet
… and you can of course complement the above top with this little bit
of ingenuity to help cool your noggin. Not to mention it looks simply
ravishing. Available from (who else?) Hammacher Schlemmer for less than $50 US.
Plan on trekking the Sahara or braving the South East Asian heat?
Why rely on bottled water on throngs of natives to personally fan you
with palm fronds in the comfort of your Range Rover when you could pack
an air-conditioner … right in your shirt?
Previously unavailable in the U.S. until this year, this odd little bit of clothing is available for just $159 via Japan Trend Shop.
The “Breathe Air” helmet was created to filter out
particles that irritate hay fever and asthma sufferers. It covers the
cyclist’s nose and mouth with a shield behind which the filtered air
circulates.
Okay, so it’s not entirely useless. But do you really want to look
like a Star Wars Stormtrooper defending the Death Star while you’re
cycling around Phuket? Currently unavailable. Expected to retail for £100.
New compounds may treat depression rapidly with few side effects
New approach could revolutionize treatment
Date:
July 13, 2015
Source:
University of Maryland School of Medicine
Summary:
A new study has identified promising compounds
that could successfully treat depression in less than 24 hours with few
side effects. The compounds could offer significant advantages over
current antidepressant medications.
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FULL STORY
A new study by researchers at
University of Maryland School of Medicine has identified promising
compounds that could successfully treat depression in less than 24 hours
while minimizing side effects. Although they have not yet been tested
in people, the compounds could offer significant advantages over current
antidepressant medications.
The research, led by Scott Thompson, PhD, Professor and Chair of the
Department of Physiology at the University of Maryland School of
Medicine (UM SOM), was published this month in the journal Neuropsychopharmacology.
"Our results open up a whole new class of potential antidepressant
medications," said Dr. Thompson. "We have evidence that these compounds
can relieve the devastating symptoms of depression in less than one day,
and can do so in a way that limits some of the key disadvantages of
current approaches."
Currently, most people with depression take medications that increase
levels of the neurochemical serotonin in the brain. The most common of
these drugs, such as Prozac and Lexapro, are selective serotonin
reuptake inhibitors, or SSRIs. Unfortunately, SSRIs are effective in
only a third of patients with depression. In addition, even when these
drugs work, they typically take between three and eight weeks to relieve
symptoms. As a result, patients often suffer for months before finding a
medicine that makes them feel better. This is not only emotionally
excruciating; in the case of patients who are suicidal, it can be
deadly. Better treatments for depression are clearly needed.
Dr. Thompson and his team focused on another neurotransmitter besides
serotonin, an inhibitory compound called GABA. Brain activity is
determined by a balance of opposing excitatory and inhibitory
communication between brain cells. Dr. Thompson and his team argue that
in depression, excitatory messages in some brain regions are not strong
enough. Because there is no safe way to directly strengthen excitatory
communication, they examined a class of compounds that reduce the
inhibitory messages sent via GABA. They predicted that these compounds
would restore excitatory strength. These compounds, called GABA-NAMs,
minimize unwanted side effects because they are precise: they work only
in the parts of the brain that are essential for mood.
The researchers tested the compounds in rats that were subjected to
chronic mild stress that caused the animals to act in ways that resemble
human depression. Giving stressed rats GABA-NAMs successfully reversed
experimental signs of a key symptom of depression, anhedonia, or the
inability to feel pleasure. Remarkably, the beneficial effects of the
compounds appeared within 24 hours -- much faster than the multiple
weeks needed for SSRIs to produce the same effects.
"These compounds produced the most dramatic effects in animal studies
that we could have hoped for," Dr. Thompson said. "It will now be
tremendously exciting to find out whether they produce similar effects
in depressed patients. If these compounds can quickly provide relief of
the symptoms of human depression, such as suicidal thinking, it could
revolutionize the way patients are treated."
In tests on the rats' brains, the researchers found that the
compounds rapidly increased the strength of excitatory communication in
regions that were weakened by stress and are thought to be weakened in
human depression. No effects of the compound were detected in unstressed
animals, raising hopes that they will not produce side effects in human
patients.
"This work underscores the importance of basic research to our
clinical future," said Dean E. Albert Reece, MD, PhD, MBA, who is also
the vice president for Medical Affairs, University of Maryland, and the
John Z. and Akiko K. Bowers Distinguished Professor and Dean of the
School of Medicine. "Dr. Thompson's work lays the crucial groundwork to
transform the treatment of depression and reduce the tragic loss of
lives to suicide."
Jonathan Fischell, Adam M Van Dyke, Mark D Kvarta, Tara A LeGates, Scott M Thompson. Rapid
Antidepressant Action and Restoration of Excitatory Synaptic Strength
After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA
Receptors. Neuropsychopharmacology, 2015; DOI: 10.1038/npp.2015.112
University
of Maryland School of Medicine. "New compounds may treat depression
rapidly with few side effects: New approach could revolutionize
treatment." ScienceDaily. ScienceDaily, 13 July 2015.
<www.sciencedaily.com/releases/2015/07/150713131349.htm>.
New drug may treat depression in 24 hours
By PTI | 14 Jul, 2015, 05.14PM IST
3 comments |Post a Comment
READ MORE ON » University of Maryland School of Medicine | Thompson Professor | stress | Scott Thompson | professor and chair | ..
Optical collision between galaxies NGC 2207 and IC 2163.Image:Stuart Rankin
Galaxy collison favours bigger guy
Larger galaxy forms stars at expense of smaller galaxy
Milkyway and Andromeda to collide in four billion years
WHO IS the winner when two galaxies hurtling towards each other on a collision course through space smash together?
The collision of cosmic proportions was considered by researchers at
the International Centre for Radio Astronomy Research (ICRAR) who
determined that the bigger guy always comes out on top.
Previously, astronomers thought that when two galaxies smash into
each other their gas clouds get churned up and seed the birth of stars
much faster than if they remained separate.
However, research headed by astrophysicist Dr Luke Davies, from the UWA node of ICRAR, suggests the outcome depends on the size of each galaxy.
“When two ‘giants’ collide, they both increase their stellar birth
rate, but when one galaxy significantly outweighs the other, the ‘giant’
begins rapidly forming new stars, whereas the ‘dwarf’ suddenly
struggles to make any at all,” he says.
Dr Davies says the different outcome is likely due to how long the collisions take to happen.
He says when two ‘giants’ get close they smash into each other very
quickly and form a single galaxy before they use up all of their gas. An animation of galaxies colliding. Credit: ICRAR
But when a ‘giant’ and ‘dwarf’ meet they take a very long time to
actually reach each other, and the longer collision timescale means they
have time to use up all of their star-forming gas and stop making new
stars.
“I like to think of this as the dwarf staying out of arms reach of
the giant for a long time, but running around so much that they
eventually run out of steam—while the two giants just smash straight
into each other in a flurry,” he says.
Dr Davies has studied more than 20,000 merging galaxies as part of the Galaxy and Mass Assembly (GAMA) survey.
“GAMA accurately measures the positions in space of hundreds of
thousands of galaxies, so we can work out which ones are very close and
more likely to collide in the near future,” Dr Davies says.
“The light emitted from these galaxies is measured at lots of
different wavelengths, and from that we can work out their
characteristics, such as how many stars they have and how fast they are
forming new stars.”
Dr Davies says the Milky Way and our nearest neighbour, Andromeda,
are like ‘cosmic tanks’ on a collision course, and in about four billion
years they will merge to become a new galaxy Milkdromeda.
Notes
ICRAR is a joint venture between Curtin University and the University
of Western Australia with support and funding from the State Government
of Western Australia.
Jan 14, 2014 - Milky Way's mysterious black hole set to gobble up giant gas cloud. The gas cloud, named G2, is due to collide with the black hole in March; When it ..... images show unexplained 'complex' shapes on the dwarf planet ahead.