A compound may restore memory loss in Alzheimer’s
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WASHINGTON: Scientists including an Indian-origin researcher have
discovered a new compound that can restore memory loss and reverse
symptoms in Alzheimer's.
Researchers from the National Institutes of Health in the US found that when a molecule called TFP5 is injected into mice with disease that is the equivalent of human Alzheimer's , symptoms are reversed and memory is restored — without obvious toxic side effects.
"We hope that clinical trial studies in Alzheimer's patients should yield an extended and a better quality of life as observed in mice upon TFP5 treatment," said senior researcher Harish C Pant. "Therefore, we suggest that TFP5 should be an effective therapeutic compound."
Pant and colleagues used mice with a disease considered the equivalent of Alzheimer's . One set was injected with the small molecule TFP5, while the other was injected with saline as placebo.
The mice, after a series of intraperitoneal injections of TFP5, displayed a substantial reduction in the various disease symptoms along with restoration of memory loss. In addition, the mice with TFP5 injections experienced no weight loss, neurological stress or signs of toxicity.
The disease in placebo mice progressed normally.
Researchers from the National Institutes of Health in the US found that when a molecule called TFP5 is injected into mice with disease that is the equivalent of human Alzheimer's , symptoms are reversed and memory is restored — without obvious toxic side effects.
"We hope that clinical trial studies in Alzheimer's patients should yield an extended and a better quality of life as observed in mice upon TFP5 treatment," said senior researcher Harish C Pant. "Therefore, we suggest that TFP5 should be an effective therapeutic compound."
Pant and colleagues used mice with a disease considered the equivalent of Alzheimer's . One set was injected with the small molecule TFP5, while the other was injected with saline as placebo.
The mice, after a series of intraperitoneal injections of TFP5, displayed a substantial reduction in the various disease symptoms along with restoration of memory loss. In addition, the mice with TFP5 injections experienced no weight loss, neurological stress or signs of toxicity.
The disease in placebo mice progressed normally.
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